RESEARCH

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Principles of Health Research Methodology
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[ms_accordion_item title=”Coordination” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]Matilde Monteiro Soares
Luís Filipe Azevedo
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Health Research aims to respond to issues in clinical medicine and health of populations, contributing to the knowledge and decision making. The issues addressed in this area concern the study of diagnosis, treatment, prognosis, etiology and prevention of the disease and to study the frequency of phenomena and associated entities.
Understanding the fundamentals of scientific methodology and the development of a set of basic skills becomes in this context essential to the achievement of quality research work.
At the end of this curricular unit students should be able to: (1) design a health research project (2) to critically assess the results of health research, particularly in the context of its application to decision making.
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Science and Medicine. A step-by-step guide to Clinical and Health Services Research. Formulation of the research question. Bibliographic review. Study design (Definitions and classification; Experimental studies: Clinical trials; Observational studies; Diagnostic tests studies). Frequency, association and impact measures. Precision and validity, random and systematic errors. Selection of participants (sampling and sample size; bias in selection of participants). Selection of methods and instruments for data collection (reproducibility and validity of instruments; design and validation of questionnaires; bias in data collection). Writing a research protocol. Collecting, processing and analyzing data.
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The syllabus includes all necessary and sufficient basic concepts and practical competencies to allow the students to plan, execute and critically appraise biomedical research work. A critical attitude and judgment, as well as a systematic and scientifically adequate approach, will be promoted regarding scientific evidence. Thus, there is an intimate relation between the syllabus and the intended learning outcomes of the curricular unit.
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Theoretical and practical classes and tutorial orientation.
An e-learning platform will be used to support theoretical and practical classes.
Course evaluation will be based on a practical work and a final theoretical exam, with a weighting of 20% and 80% of the final grade, respectively. The final theoretical exam will cover the theoretical content of the course and will include: (a) closed choice questions, simple and multiple and (b) open questions with short and long answers. The final exam will have a duration of 90 minutes.
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Theoretical lectures are an efficient method for transmitting the theoretical topics included in the course, while hands-on practical lessons allow a solid development of competencies needed for a proper integration of these topics and the promotion of a critical attitude regarding scientific evidence and, in particular, the execution and critical appraisal of biomedical research work.
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Hulley, S.B., Cummings, S.R., Browner, W.S., Grady, D. G., & Newman, T. B. (2013). Designing Clinical Research (4th edition). Philadelphia: Lippincott Williams and Wilkins
Fletcher, R., & Fletcher, S.W. (2014) Clinical Epidemiology: The Essentials (5th Edition). Philadelphia: Lippincott Williams and Wilkins
Haynes, R.B., Sackett, D.L., Guyatt, G.H., & Tugwell, P. (2006). Clinical epidemiology: how to do clinical practice research (3rd edition). Philadelphia: Lippincott Williams & Wilkins
Lopes, R.D. & Harrington, R. A. (2013). Understanding Clinical Research. New York: McGraw-Hill Education.
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